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Niacin (Nicotinic acid)

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Niacin (Nicotinic acid) is used for improving cholesterol levels reducing the risk for a second heart attack slowing or treating hardening of the arteries and lowering very high serum triglyceride levels. It is used in combination with diet. It may be used alone or with other medicines. Niacin (Nicotinic acid) is an antihyperlipidemic. It works by reducing low-density lipoprotein ('bad') cholesterol and triglycerides and increasing high-density lipoprotein ('good') cholesterol.

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About Niacin (Nicotinic acid):

Product Type: Cholesterol

Brand name: Niacin Generic name: Nicotinic acid Niacin (Nicotinic acid) is used for: Improving cholesterol levels reducing the risk for a second heart attack slowing or treating hardening of the arteries and lowering very high serum triglyceride levels. It is used in combination with diet. It may be used alone or with other medicines. It may also be used for other conditions as determined by your doctor. Niacin (Nicotinic acid) is an antihyperlipidemic. It works by reducing low-density lipoprotein (“bad”) cholesterol and triglycerides and increasing high-density lipoprotein (“good”) cholesterol. Do NOT use Niacin (Nicotinic acid) if: • you are allergic to any ingredient in Niacin (Nicotinic acid) • you have severe or unexplained liver problems an active peptic ulcer or a history of arterial bleeding Contact your doctor or health care provider right away if any of these apply to you. Before using Niacin (Nicotinic acid): Some medical conditions may interact with Niacin (Nicotinic acid). Tell your doctor or pharmacist if you have any medical conditions especially if any of the following apply to you: • if you are pregnant planning to become pregnant or are breast-feeding • if you are taking any prescription or nonprescription medicine herbal preparation or dietary supplement • if you have allergies to medicines foods or other substances • if you have a history of chest pain diabetes gallbladder problems glaucoma gout heart problems or a recent heart attack kidney or liver problems low blood pressure low phosphate levels muscle problems (eg rhabdomyolysis) stomach problems (eg peptic ulcers) or thyroid problems • if you have a history of bleeding problems or are taking anticoagulants (eg warfarin) • if you consume large amounts of alcohol Some MEDICINES MAY INTERACT with Niacin (Nicotinic acid). Tell your health care provider if you are taking any other medicines especially any of the following: • Anticoagulants (eg warfarin) because side effects such as bleeding may occur • Fibrates (eg gemfibrozil fenofibrate) or HMG-CoA reductase inhibitors (“statins”) (eg simvastatin) because side effects such as serious muscle aches and weakness that may be a symptom of a serious medical condition called rhabdomyolysis may occur • Medicine for high blood pressure (eg diltiazem) or angina (eg nitroglycerin) because side effects such as dizziness upon standing and very low blood pressure may be increased by Niacin (Nicotinic acid) • Alcohol because toxic effects such as delirium or lactic acidosis may occur This may not be a complete list of all interactions that may occur. Ask your health care provider if Niacin (Nicotinic acid) may interact with other medicines that you take. Check with your health care provider before you start stop or change the dose of any medicine. How to use Niacin (Nicotinic acid): Use Niacin (Nicotinic acid) as directed by your doctor. Check the label on the medicine for exact dosing instructions. • To minimize flushing and upset stomach take Niacin (Nicotinic acid) at bedtime after a low-fat snack (eg low-fat yogurt banana crackers with a glass of milk) unless your doctor directs otherwise. Do not take Niacin (Nicotinic acid) with alcohol a hot drink or spicy foods. • Do not take bile acid sequestrants (eg colestipol cholestyramine) within 4 to 6 hours of taking Niacin (Nicotinic acid). • If you miss a dose of Niacin (Nicotinic acid) take it as soon as possible. If it is almost time for the next dose skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Ask your health care provider any questions you may have about how to use Niacin (Nicotinic acid). Important safety information: • Niacin (Nicotinic acid) may cause dizziness or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Niacin (Nicotinic acid) with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it. • Niacin (Nicotinic acid) may cause dizziness; alcohol hot weather exercise or fever may increase this effect. To prevent it sit up or stand slowly especially in the morning. Sit or lie down at the first sign of this effect. • Do NOT take more than the recommended dose without checking with your doctor. • Niacin (Nicotinic acid) may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark tarry or bloody stools. • Do not substitute Niacin (Nicotinic acid) for any other type of niacin without talking with your doctor. Severe liver damage can occur. • If you stop taking Niacin (Nicotinic acid) for an extended period contact your doctor before you start taking it again. Your dose may need to be adjusted. • Flushing occurs with Niacin (Nicotinic acid) and may last for several hours. Talk with your doctor if flushing becomes bothersome. • Take Niacin (Nicotinic acid) at bedtime so that flushing will occur during sleep. If you are awakened by flushing at night get up slowly especially if you feel dizzy or faint or if you are taking blood thinners. Take aspirin or a nonsteroidal anti-inflammatory drug (NSAID) (eg ibuprofen) 30 minutes before taking Niacin (Nicotinic acid) to lessen flushing. • Diabetes patients — Niacin (Nicotinic acid) may cause the results of some tests for urine glucose to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine. • Do not take large doses of vitamins while you use Niacin (Nicotinic acid) unless your doctor tells you to. • Report any unexplained muscle pain tenderness or weakness to your doctor right away especially if you also have a fever or general body discomfort. • Niacin (Nicotinic acid) may interfere with certain lab tests including plasma or urinary catecholamine tests or urine glucose tests. Be sure your doctor and lab personnel know you are taking Niacin (Nicotinic acid). • Lab tests including liver function tests blood glucose and serum creatine kinase tests may be performed while you use Niacin (Nicotinic acid). These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments. • Niacin (Nicotinic acid) should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed. • PREGNANCY and BREAST-FEEDING: If you become pregnant contact your doctor. You will need to discuss the benefits and risks of using Niacin (Nicotinic acid) while you are pregnant. It is not known if Niacin (Nicotinic acid) is found in breast milk. Do not breast-feed while taking Niacin (Nicotinic acid). Possible side effects of Niacin (Nicotinic acid): All medicines may cause side effects but many people have no or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome: • Diarrhea; dizziness; headache; heartburn; increased cough indigestion or upset stomach; nausea; temporary skin redness itching tingling or feelings of warmth (flushing); vomiting. Seek medical attention right away if any of these SEVERE side effects occur: • Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth face lips or tongue; unusual hoarseness); black tarry or bloody stools; changes in vision (eg cloudy or blurred vision); decrease in urine or dark-colored urine; fainting; fast or irregular heartbeat; flu-like symptoms (eg chills fever persistent sore throat); increased sweating; loss of appetite; muscle pain tenderness swelling or weakness (with or without fever and fatigue); numbness or persistent tingling of the skin; severe dizziness or headache; severe or persistent diarrhea nausea or vomiting; shortness of breath; stomach pain; swelling of the hands legs or feet; unusual bruising or bleeding; vomit that looks like coffee grounds; yellowing of the skin or eyes. This is not a complete list of all side effects that may occur. If you have questions about side effects contact your health care provider. Call your doctor for medical advice about side effects. If OVERDOSE is suspected: • Symptoms may include flushing. Proper storage of Niacin (Nicotinic acid): Store Niacin (Nicotinic acid) at room temperature between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat moisture and light. Do not store in the bathroom. Keep Niacin (Nicotinic acid) out of the reach of children and away from pets.

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