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No Prescription Meds and Arthritis » Prescription Drugs 5 » Dantrium Generic Dantrolene IndicationsDANTRIUM is indicated in controlling the manifestations of clinical spasticity resulting from serious chronic disorders such as spinal cord injury stroke cerebral palsy or multiple sclerosis. It is of particular benefit to the patient whose functional rehabilitation has been retarded by the sequelae of spasticity. Such patients must have presumably reversible spasticity where relief of spasticity will aid in restoring residual function. There is no evidence that patients with contractures will benefit. DANTRIUM is not indicated in the treatment of skeletal muscle spasm resulting from rheumatic disorders or electroconvulsive therapy.If improvement occurs it will ordinarily occur within the dosage titration schedule (see DOSAGE AND ADMINISTRATION) as manifested by a decrease in the severity of spasticity and the ability to resume a daily function not quite attainable without DANTRIUM.Occasionally subtle but meaningful improvements in spasticity may occur with DANTRIUM therapy. In such instances information regarding improvement should be solicited from the patient and those who are in constant daily contact and attendance with him. Brief withdrawal of DANTRIUM for a period of 2 to 4 days will frequently demonstrate exacerbation of the manifestation of spasticity and may serve to confirm a clinical impression.A decision to continue the administration of DANTRIUM on a long term basis is justified if introduction of the drug into the patient's regimen produces a significant reduction in painful and/or disabling spasticity such as clonus or permits a significant reduction in the intensity and/or degree of nursing care required or rids the patient of an annoying manifestation of spasticity considered important by the patient himself.Dosage and Administration:Prior to the administration of DANTRIUM consideration should be given to the potential response to treatment. A decrease in spasticity sufficient to allow a daily function not otherwise attainable should be the therapeutic goal of treatment with DANTRIUM. Refer to the INDICATIONS section for a description of the response to be anticipated.It is important to establish a therapeutic goal (regain and maintain a specific function such as therapeutic exercise program utilisation of braces transfer manoeuvres etc.) before beginning DANTRIUM therapy. Dosage should be increased until the maximum performance compatible with the dysfunction due to underlying disease is achieved. No further increase in dosage is then indicated.Usual Dosage It is important that the dosage be titrated and individualised for maximum effect. The lowest dose compatible with optimal response is recommended.In view of the potential for liver damage in long-term DANTRIUM use therapy should be stopped if benefits are not evident within 45 days.Adults Begin therapy with 25 mg once daily; increase to 25 mg two three or four times daily and then by increments of 25 mg up to as high as 50 mg two three or four times daily if necessary. The maximum recommended dose is 200 mg/day. As most patients will respond to this or a lower dose and hepatotoxicity appears to be dose-related above 200 mg/day higher doses should be used only rarely and with close monitoring. (See WARNINGS). Doses higher than 400 mg/day should not be used.Each dosage level should be maintained for four to seven days to determine the patient's response. The dose should not be increased beyond and may even have to be reduced to the amount at which the patient received maximal benefit without adverse effects.Children A similar approach should be utilised starting with 0.5 mg/kg of body weight twice daily; this is increased to 0.5 mg/kg three or four times daily and then by increments to a maximum of 2 mg/kg three times a day. Doses higher than 50 mg four times daily should not be used in children. Buy Dantrium Generic Dantrolene and other Prescription Drugs 5 products online at Medstore. Buy Online at Medstore - Click Here!
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View more Prescription Drugs 5 No Prescription Meds and Arthritis: Arava (Leflunomide) Arava (Leflunomide) is a pyrimidine synthesis inhibitor used to treat rheumatoid arthritis. This medicine may be used to reduce the signs and symptoms of rheumatoid arthritis slow the development of damage to the joints and to improve physical function. Buy Arava (Leflunomide) and other Arthritis products online at Medstore. About Arava (Leflunomide): Product Type: Arthritis Brand name: Arava Generic name: Leflunomide What is the most important information I should know about Arava? • Arava is in the FDA pregnancy category X. There is an increased risk of birth defects and death of the unborn baby while taking Arava. Do not take this medication if you are pregnant or could become pregnant during treatment. Notify your doctor immediately if you think you have become pregnant during treatment. Birth control must be used during treatment with Arava. Discuss with your doctor the procedure for removing Arava from the body following treatment before becoming pregnant. Without the proper drug elimination procedure it may take up to two years before Arava is at sufficiently low levels in the body so as to reduce the risk of harm to an unborn baby. It is not known whether Arava imposes an increased risk of fetal harm when taken by a man. Men wishing to father a child while taking Arava should discuss their options with their doctor. What is Arava? • Arava affects the immune system and decreases inflammation. • Arava is used to reduce the signs and symptoms of rheumatoid arthritis reduce damage to the joints caused by rheumatoid arthritis and to improve physical function in people with rheumatoid arthritis. • Arava may also be used for purposes other than those listed in this medication guide. What should I discuss with my healthcare provider before taking Arava? • Before taking Arava tell your doctor if you have liver disease or a history of hepatitis; a history of significant alcohol use; kidney disease; an immune system disease; recently received a live vaccine; poor bone marrow function; or a current or chronic infection. • You may not be able to take Arava or you may require a dosage adjustment or special monitoring during your treatment if you have any of the conditions listed above. • Arava is in the FDA pregnancy category X. There is an increased risk of birth defects and death of the unborn baby while taking Arava. Do not take this medication if you are pregnant or could become pregnant during treatment. Notify your doctor immediately if you think you have become pregnant during treatment. Birth control must be used during treatment with Arava. Discuss with your doctor the procedure for removing Arava from the body following treatment before becoming pregnant. Without the proper drug elimination procedure it may take up to two years before Arava is at sufficiently low levels in the body so as to reduce the risk of harm to an unborn baby. It is not known whether Arava imposes an increased risk of fetal harm when taken by a man. Men wishing to father a child while taking Arava should discuss their options with their doctor. • It is not known whether Arava passes into breast milk. There is a potential for serious side effects in a nursing baby from Arava. Do not take Arava if you are breast-feeding a baby. How should I take Arava? • Take Arava exactly as directed by your doctor. If you do not understand these instructions ask your pharmacist nurse or doctor to explain them to you. • Take each dose with a full glass of water. • Arava can be taken with or without food or milk. • It is important to take Arava regularly to get the most benefit. • Your doctor may want you to have blood tests or other medical evaluations while taking Arava to monitor side effects and progress. • Store Arava at room temperature away from moisture and heat. What happens if I miss a dose? • Take the missed dose as soon as you remember. If it is almost time for your next dose skip the missed dose and only take your next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor. What happens if I overdose? • Seek emergency medical attention if an overdose is suspected. • Symptoms of a Arava overdose may include diarrhea abdominal pain blood problems and liver problems. What should I avoid while taking Arava? • Discuss with your doctor the use of alcohol while taking Arava. Alcohol and Arava can both be damaging to the liver. • Arava can lower the activity of the immune system making you more susceptible to infection. Avoid contact with people who have colds the flu or other contagious illnesses. In addition do not receive vaccines that contain a live strain of the virus (e.g. live oral polio vaccine) and avoid contact with individuals who have recently been vaccinated with a live virus. What are the possible side effects of Arava? • If you experience any of the following serious side effects stop taking Arava and seek medical treatment or contact your doctor immediately: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips tongue or face; or hives); changes in liver function (may be detected by blood tests or cause symptoms such as yellowing of the skin or eyes; pale colored stools or dark colored urine; unusual fatigue; or abdominal pain); decreased bone marrow function or blood problems (may be detected by blood tests or cause symptoms such as extreme or unusual fatigue; easy bruising or bleeding; black bloody or tarry stools; fever or chills; or signs of infection such as fever; chills or sore throat); or skin rash; or sores in the mouth. • Other less serious side effects may be more likely to occur. Continue to take Arava and talk to your doctor if you experience headache; increased blood pressure; muscle aches; nausea; diarrhea; or hair loss. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. What other drugs will affect Arava? • Before taking Arava tell your doctor if you are taking any of the following drugs: cholestyramine (Questran Prevalite LoCHOLEST); methotrexate (Rheumatrex); or rifampin (Rifadin Rimactane). • You may not be able to take Arava or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above. • Drugs other than those listed here may also interact with Arava. 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