No Prescription Meds and Arthritis » Blood Pressure » Avalide (Irbesartan + Hydrochlorothiazide)
Avalide (Irbesartan + Hydrochlorothiazide) is used for treating high blood pressure. Avalide (Irbesartan + Hydrochlorothiazide) is a combination angiotensin II receptor blocker and diuretic. The angiotensin II receptor blocker works by relaxing the blood vessels. Exactly how the diuretic works to decrease blood pressure is unknown but it helps the kidneys to eliminate fluid and sodium from the body.
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About Avalide (Irbesartan + Hydrochlorothiazide):
Product Type: Blood Pressure
Brand name: Avalide
Generic name: Irbesartan + Hydrochlorothiazide
Avalide (Irbesartan + Hydrochlorothiazide) is used for:
Treating high blood pressure. It may also be used for other conditions as determined by your doctor.
Avalide (Irbesartan + Hydrochlorothiazide) is a combination angiotensin II receptor blocker and diuretic. The angiotensin II receptor blocker works by relaxing the blood vessels. Exactly how the diuretic works to decrease blood pressure is unknown but it helps the kidneys to eliminate fluid and sodium from the body.
Do NOT use Avalide (Irbesartan + Hydrochlorothiazide) if:
• you are allergic to any ingredient in Avalide (Irbesartan + Hydrochlorothiazide) or to any other sulfonamide medicine (eg sulfamethoxazole)
• you are pregnant
• you have severe kidney problems or are unable to urinate
• you are taking dofetilide or ketanserin
Contact your doctor or health care provider right away if any of these apply to you.
Before using Avalide (Irbesartan + Hydrochlorothiazide):
Some medical conditions may interact with Avalide (Irbesartan + Hydrochlorothiazide). Tell your doctor or pharmacist if you have any medical conditions especially if any of the following apply to you:
• if you are planning to become pregnant or are breast-feeding
• if you are taking any prescription or nonprescription medicine herbal preparation or dietary supplement
• if you have allergies to medicines foods or other substances
• if you have ever had a severe reaction (eg swelling of the hands face lips eyes throat or tongue; trouble swallowing or breathing; hoarseness) after taking any other angiotensin II receptor blocker or an angiotensin converting enzyme (ACE) inhibitor (eg captopril)
• if you are dehydrated; have low blood volume; have low blood sodium chloride potassium or magnesium levels; or have high blood calcium levels
• if you have asthma; diabetes; gout; heart problems (eg congestive heart failure); liver gall bladder or kidney problems; high blood cholesterol or lipid levels; or systemic lupus erythematosus
• if you have recently had nerve surgery
Some MEDICINES MAY INTERACT with Avalide (Irbesartan + Hydrochlorothiazide). Tell your health care provider if you are taking any other medicines especially any of the following:
• Dofetilide or ketanserin because the risk of irregular heartbeat may be increased
• Adrenocorticotropic hormone (ACTH) barbiturates (eg phenobarbital) corticosteroids (eg prednisone) diuretics (eg furosemide) narcotic pain medicines (eg morphine) or other medicines for high blood pressure because they may increase the risk of Avalide (Irbesartan + Hydrochlorothiazide)'s side effects
• Cholestyramine colestipol or nonsteroidal anti-inflammatory drugs (NSAIDs) (eg ibuprofen) because they may decrease Avalide (Irbesartan + Hydrochlorothiazide)'s effectiveness
• Diazoxide digoxin lithium nondepolarizing muscle relaxants (eg tubocurarine) potassium or potassium-sparing diuretics (eg spironolactone) because risk of their side effects and toxic effects may be increased by Avalide (Irbesartan + Hydrochlorothiazide)
• Diabetes medicine (eg glipizide metformin) insulin or pressor amines (eg norepinephrine) because their effectiveness may be decreased by Avalide (Irbesartan + Hydrochlorothiazide)
This may not be a complete list of all interactions that may occur. Ask your health care provider if Avalide (Irbesartan + Hydrochlorothiazide) may interact with other medicines that you take. Check with your health care provider before you start stop or change the dose of any medicine.
How to use Avalide (Irbesartan + Hydrochlorothiazide):
Use Avalide (Irbesartan + Hydrochlorothiazide) as directed by your doctor. Check the label on the medicine for exact dosing instructions. Check the label on the medicine for exact dosing instructions.
• Avalide (Irbesartan + Hydrochlorothiazide) may be taken with or without food.
• Drinking extra fluids while you are taking Avalide (Irbesartan + Hydrochlorothiazide) is recommended. Check with your doctor for instructions.
• Avalide (Irbesartan + Hydrochlorothiazide) may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep try to take your dose before 6 pm.
• If you take cholestyramine or colestipol ask your doctor or pharmacist how to take it with Avalide (Irbesartan + Hydrochlorothiazide).
• Continue to take Avalide (Irbesartan + Hydrochlorothiazide) even if you feel well. Do not miss any doses.
• If you miss a dose of Avalide (Irbesartan + Hydrochlorothiazide) take it as soon as possible. If it is almost time for your next dose skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Avalide (Irbesartan + Hydrochlorothiazide).
Important safety information:
• Avalide (Irbesartan + Hydrochlorothiazide) may cause drowsiness dizziness or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Avalide (Irbesartan + Hydrochlorothiazide) with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Avalide (Irbesartan + Hydrochlorothiazide) may cause dizziness lightheadedness or fainting; alcohol hot weather exercise or fever may increase these effects. To prevent them sit up or stand slowly especially in the morning. Sit or lie down at the first sign of any of these effects.
• Report any lightheadedness or fainting to your doctor immediately. Your risk of lightheadedness or fainting may be increased if you experience diarrhea vomiting excessive sweating if you do not drink enough fluids or if you are on a low-salt diet.
• Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel normal. Tell your doctor if you develop any new symptoms.
• Avalide (Irbesartan + Hydrochlorothiazide) may cause you to become sunburned more easily. Avoid the sun sunlamps or tanning booths until you know how you react to Avalide (Irbesartan + Hydrochlorothiazide). Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
• Tell your doctor or dentist that you take Avalide (Irbesartan + Hydrochlorothiazide) before you receive any medical or dental care emergency care or surgery.
• If you have high blood pressure do not use nonprescription products that contain stimulants. These products may include diet pills or cold medicines. Contact your doctor if you have any questions or concerns.
• Your doctor may have also prescribed a potassium supplement for you. If so follow the dosing carefully. Do not start taking additional potassium on your own or change your diet to include more potassium without first checking with your doctor.
• Check with your doctor before you use a salt substitute or a product that has potassium in it.
• Diabetes patients — Avalide (Irbesartan + Hydrochlorothiazide) may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
• Avalide (Irbesartan + Hydrochlorothiazide) may raise your blood sugar. High blood sugar may make you feel confused drowsy or thirsty. It can also make you flush breathe faster or have a fruit-like breath odor. If these symptoms occur tell your doctor right away.
• Avalide (Irbesartan + Hydrochlorothiazide) may interfere with certain lab tests including parathyroid function tests. Be sure your doctor and lab personnel know you are taking Avalide (Irbesartan + Hydrochlorothiazide).
• Lab tests including kidney function blood pressure and blood electrolytes may be performed while you use Avalide (Irbesartan + Hydrochlorothiazide). These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
• Use Avalide (Irbesartan + Hydrochlorothiazide) with caution in the ELDERLY; they may be more sensitive to its effects.
• Avalide (Irbesartan + Hydrochlorothiazide) should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: Avalide (Irbesartan + Hydrochlorothiazide) may cause birth defects or fetal death if you take it while you are pregnant. If you think you may be pregnant contact your doctor right away. Avalide (Irbesartan + Hydrochlorothiazide) is found in breast milk. Do not breast-feed while taking Avalide (Irbesartan + Hydrochlorothiazide).
Possible side effects of Avalide (Irbesartan + Hydrochlorothiazide):
All medicines may cause side effects but many people have no or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
• Dizziness; nausea; tiredness; vomiting.
Seek medical attention right away if any of these SEVERE side effects occur:
• Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth face lips or tongue); chest pain; confusion; decrease in sexual ability; depression; drowsiness; fainting; fast or irregular heartbeat; fever chills or persistent sore throat; decreased urination; hoarseness; muscle pain tenderness or cramps; red swollen blistered or peeling skin; restlessness; seizures; severe or persistent dry mouth; severe or persistent vomiting; shortness of breath; swelling of the arms or legs; unusual bruising or bleeding; unusual thirst; unusual tiredness or weakness; yellowing of the skin or eyes.
If OVERDOSE is suspected:
Symptoms may include confusion; fainting; fast slow or irregular heartbeat; severe or unusual dizziness.
Proper storage of Avalide (Irbesartan + Hydrochlorothiazide):
Store Avalide (Irbesartan + Hydrochlorothiazide) at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat moisture and light. Do not store in the bathroom. Keep Avalide (Irbesartan + Hydrochlorothiazide) out of the reach of children and away from pets
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Irbesartan + Hydrochlorothiazide Avalide

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Without the proper drug elimination procedure it may take up to two years before Arava is at sufficiently low levels in the body so as to reduce the risk of harm to an unborn baby. It is not known whether Arava imposes an increased risk of fetal harm when taken by a man. Men wishing to father a child while taking Arava should discuss their options with their doctor. • It is not known whether Arava passes into breast milk. There is a potential for serious side effects in a nursing baby from Arava. Do not take Arava if you are breast-feeding a baby. How should I take Arava? • Take Arava exactly as directed by your doctor. If you do not understand these instructions ask your pharmacist nurse or doctor to explain them to you. • Take each dose with a full glass of water. • Arava can be taken with or without food or milk. • It is important to take Arava regularly to get the most benefit. • Your doctor may want you to have blood tests or other medical evaluations while taking Arava to monitor side effects and progress. • Store Arava at room temperature away from moisture and heat. What happens if I miss a dose? • Take the missed dose as soon as you remember. If it is almost time for your next dose skip the missed dose and only take your next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor. What happens if I overdose? • Seek emergency medical attention if an overdose is suspected. • Symptoms of a Arava overdose may include diarrhea abdominal pain blood problems and liver problems. What should I avoid while taking Arava? • Discuss with your doctor the use of alcohol while taking Arava. Alcohol and Arava can both be damaging to the liver. • Arava can lower the activity of the immune system making you more susceptible to infection. Avoid contact with people who have colds the flu or other contagious illnesses. In addition do not receive vaccines that contain a live strain of the virus (e.g. live oral polio vaccine) and avoid contact with individuals who have recently been vaccinated with a live virus. What are the possible side effects of Arava? • If you experience any of the following serious side effects stop taking Arava and seek medical treatment or contact your doctor immediately: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips tongue or face; or hives); changes in liver function (may be detected by blood tests or cause symptoms such as yellowing of the skin or eyes; pale colored stools or dark colored urine; unusual fatigue; or abdominal pain); decreased bone marrow function or blood problems (may be detected by blood tests or cause symptoms such as extreme or unusual fatigue; easy bruising or bleeding; black bloody or tarry stools; fever or chills; or signs of infection such as fever; chills or sore throat); or skin rash; or sores in the mouth. • Other less serious side effects may be more likely to occur. Continue to take Arava and talk to your doctor if you experience headache; increased blood pressure; muscle aches; nausea; diarrhea; or hair loss. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. What other drugs will affect Arava? • Before taking Arava tell your doctor if you are taking any of the following drugs: cholestyramine (Questran Prevalite LoCHOLEST); methotrexate (Rheumatrex); or rifampin (Rifadin Rimactane). • You may not be able to take Arava or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above. • Drugs other than those listed here may also interact with Arava. 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